NCT03675334

Mucoderm or Connective Tissue Graft for Treatment of Gingival Recessions

Clinical Comparison Between the Use of a Connective Tissue Graft or a Porcine Collagen Matrix (Mucoderm) for Treatment of Gingival Recessions Type 1: a Randomized Controlled Clinical Study.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Coronally advanced flap plus connective tissue graft (CTG) is the gold standard therapy for root coverage. The bioabsorbable porcine collagen matrix (CM) has been widely used in periodontal and mucogingival surgery as a substitute for CTG and has achieved similar results. The CM has the advantage of no need of a second surgical area and availability overcoming the limitations of donor site in autograft. The aim of this study is to investigate the use of Mucoderm® in root coverage procedures combined with extended coronally positioned flap (ECAF), test group (TG), in comparison to the connective tissue graft associated with the ECAF, control group (CG).

Conditions

• Gingival Recession

Interventions

Type	Name	Description
PROCEDURE	Root coverage with collagen matrix graft	at one side, the root coverage have been done with a extended flap technique and collagen matrix graft. At the other side, the same technique was performed with connective graft.
PROCEDURE	Root coverage with subepithelial connective tissue graft	at one side, the root coverage have been done with a extended flap technique and collagen matrix graft. At the other side, the same technique was performed with connective graft.
OTHER	Basic periodontal treatment	profilaxis, coronary polishing and scaling and root planning

Timeline

• Start date: 2016-04-01
• Primary completion: 2019-01-01
• Completion: 2019-01-01
• First posted: 2018-09-18
• Last updated: 2026-04-14

Locations

1 site across 1 country: Brazil