NCT03672513

Short-term Supplementation, Bone Turnover and Antioxidant Status in Menopause

Short-term Supplementation, Bone Turnover and Antioxidant Status in Postmenopausal Stage: A Placebo Controlled Study.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: Universidad de Granada · Academic / Other
• Sex: Female
• Age: 44 Years – 76 Years
• Healthy volunteers: Accepted

Summary

This is a 8-week, double-blinded, placebo-controlled, randomized intervention trial to investigate the effects of Mg and Zn supplementation on antioxidant status and bone hormonal parameters. Participants were randomly assigned to one of three treatment groups: Placebo group (PbG: 25 women); Magnesium Group - 500 mg/day of Mg (MgG: 27 women); Zinc Group - 50 mg/day of Zn (ZnG: 26 women).

Detailed description

Seventy-eight healthy postmenopausal volunteers aged between 44 and 76 were recruited once had been informed about the protocol. This is a 8-week, double-blinded, placebo-controlled, randomized intervention trial to investigate the effects of Mg and Zn supplementation on antioxidant status and bone hormonal parameters. Participants were randomly assigned to one of three treatment groups: Placebo group (PbG: 25 women); Magnesium Group - 500 mg/day of Mg (MgG: 27 women); Zinc Group - 50 mg/day of Zn (ZnG: 26 women).

Conditions

• Menopause
• Nutritional Intervention
• Bone Diseases

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Placebo Comparator	Oral administration of 1 daily capsule containing lactose
DIETARY_SUPPLEMENT	Zinc Supplement	Oral administration of 1 daily capsule containing 50 mg/day of Zn
DIETARY_SUPPLEMENT	Magnesium supplement	Oral administration of 1 daily capsule containing 500 mg/day of Magnesium

Timeline

• Start date: 2016-09-08
• Primary completion: 2017-11-01
• Completion: 2018-09-08
• First posted: 2018-09-14
• Last updated: 2018-09-14

Locations

1 site across 1 country: Spain