NCT03672357

Short and Long Outcomes Between Laparoscopic and Open Hepatectomy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: hui hou · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

LLR was applied for tumors located at the lower edge and lateral segments of the liver that could be resected more easily than posterosuperior segments. With the development of technology and the growing experience of hepatobiliary surgeons, LLR has been expanded to major liver resections, anatomical resections, and donor hepatectomies by skilled surgeons. However, due to the concerns over the risk of operative bleeding, tumor seeding and positive resection margin, the true benefit of LLR remains unclear across surgical community.

Detailed description

The 2nd International Consensus Conference on Laparoscopic Liver Resection (ICCLLR) was held in Morioka, Japan, in 2014. The new recommendations of the ICCLLR state that the outcomes of LLR are not inferior than OLR regarding to operative mortality rate and margin negativity, and are superior in decreasing postoperative complications, blood loss, and the length of the postoperative hospital stay. However, it is not clear that whether LLR is able to alleviate the impairment of liver function after hepatic resection, and there is no RCTs to compare the short and long outcomes between LLR and OLR.

Conditions

• Laparoscopic Liver Resection
• Open Liver Resection

Interventions

Type	Name	Description
PROCEDURE	Laparoscopic liver resection	Laparoscopic hepatectomy
PROCEDURE	Open liver resection	Traditional open hepatectomy

Timeline

• Start date: 2019-01-01
• Primary completion: 2024-09-01
• Completion: 2025-04-01
• First posted: 2018-09-14
• Last updated: 2018-12-13

Locations

1 site across 1 country: China