NCT03669809

The Biological Rhythm of Human Metabolite

Association Between Serum Metabolism Markers and Biological Rhythm

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Shandong Provincial Hospital · Other Government
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The circadian regulation in mammals have been known for a long time. A special group of clock genes, organized in feedback loops, are responsible for the circadian regulation in both the SCN and peripheral organs. The central clock is mainly entrained by the light-dark cycle, while the peripheral ones in organs such as liver and intestine, are more influenced by the feeding-fasting cycles. The coordination of central and peripheral clocks is thought to be essential in the maintenance of physiological homeostasis.This study aim to investigate the association between biological rhythm and metabolism.

Conditions

• Rhythm Nodal
• Metabolism and Nutrition Disorder
• Metabolism Disorder, Lipid

Timeline

• Start date: 2011-05-01
• Primary completion: 2050-05-01
• Completion: 2050-05-01
• First posted: 2018-09-13
• Last updated: 2022-05-11

Locations

1 site across 1 country: China