Trials / Terminated
TerminatedNCT03668392
Asparaginase Activity Monitoring (AAM) in Adult Patients With Acute Lymphoblastic Leukemia (ALL)
- Status
- Terminated
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 7 (actual)
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
In order to understand how pharmacokinetics and immunological inactivation affect the therapeutic efficacy of Asparaginase (ASP), it is of help and advised in the frame of clinical font-line protocols to monitor the enzymatic activity by measuring the serum ASP levels in the days following the administration of the drug.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Asparaginase | Measurement of serum Asparaginase activities during therapy, in terms of intensity and duration, as surrogate parameter for asparaginase depletion. |
Timeline
- Start date
- 2020-06-25
- Primary completion
- 2021-12-31
- Completion
- 2021-12-31
- First posted
- 2018-09-12
- Last updated
- 2022-03-16
Locations
7 sites across 1 country: Italy
Source: ClinicalTrials.gov record NCT03668392. Inclusion in this directory is not an endorsement.