Trials / Terminated
TerminatedNCT03668106
Effect of Different Sperm Processing Methods in ICSI Outcome.
Effect of Different Sperm Processing Methods ( Swim up, Zeta, Sperm Gradient Centrifugation ) in ICSI Outcome. "A Sperm DNA Perspective"
- Status
- Terminated
- Phase
- Phase 2 / Phase 3
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Benha University · Academic / Other
- Sex
- All
- Age
- 20 Years – 37 Years
- Healthy volunteers
- Not accepted
Summary
A total 180 semen samples from couples diagnosed with unexplained infertility were SDF index tested , then total 120 semen samples of patients' husbands with abnormal SDF index were randomly divided and then processed by swim up, sperm gradient centrifugation and Zeta methods. SDF and ICSI outcomes are monitored after semen processing.
Detailed description
A total 180 semen samples from couples diagnosed with unexplained infertility were SDF index tested , then total 120 semen samples of patients' husbands with abnormal SDF index were randomly divided and then processed by swim up (G1/ n=40), sperm gradient centrifugation (G2/ n=40) and Zeta (G3/ n=40) methods. SDF test was assessed by Halosperm kit, whereas sperm morphology was assessed by spermac stain according to strict criteria. Fertilization, division, blastulation, implantation and pregnancy rates will be tabulated and statistically tested.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | sperm processing method | different sperm processing method for selcting most proper sperm for ICSI |
Timeline
- Start date
- 2018-05-01
- Primary completion
- 2022-06-05
- Completion
- 2022-07-01
- First posted
- 2018-09-12
- Last updated
- 2022-09-21
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT03668106. Inclusion in this directory is not an endorsement.