Clinical Trials Directory

Trials / Terminated

TerminatedNCT03665129

IPH5401 (Anti-C5aR) in Combination With Durvalumab in Patients With Advanced Solid Tumors

A Phase I Study of the Anti-C5aR, IPH5401, in Combination With the Anti-PD-L1, Durvalumab, in Patients With Selected Advanced Solid Tumors

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
73 (actual)
Sponsor
Innate Pharma · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a multicenter, open-label, dose-escalation and dose-expansion study to evaluate the safety, tolerability, antitumor activity of IPH5401 (anti C5aR) in combination with Durvalumab (MEDI4736) in Adult Subjects with selected advanced solid tumors.

Conditions

Interventions

TypeNameDescription
BIOLOGICALIPH5401 and DurvalumabIPH5401 and durvalumab

Timeline

Start date
2018-09-07
Primary completion
2021-02-24
Completion
2021-02-24
First posted
2018-09-11
Last updated
2022-01-27

Locations

12 sites across 2 countries: United States, France

Regulatory

Source: ClinicalTrials.gov record NCT03665129. Inclusion in this directory is not an endorsement.