Clinical Trials Directory

Trials / Completed

CompletedNCT03664011

A Study in Healthy Men to Test How BI 730357 is Processed by the Body

A Phase I, Open-label, Single-dose Trial to Investigate Metabolism and Pharmacokinetics of BI 730357 BS (C-14) Administered as Oral Solution in Healthy Male Volunteers

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
6 (actual)
Sponsor
Boehringer Ingelheim · Industry
Sex
Male
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

The main objectives of the study are as follows: * To assess the mass balance recovery of (C-14) BI 730357-radioactivity (also expressed as 14C-BI 730357-EQ) in urine and faeces after a single oral dose of 50 mg BI 730357 base (BS) (C-14) in healthy male subjects * To provide plasma, urine, and faecal samples for metabolite profiling and structural identification

Conditions

Interventions

TypeNameDescription
DRUGBI 730357 mixed with [C-14]BI 730357 BSOral Solution

Timeline

Start date
2018-09-10
Primary completion
2018-11-13
Completion
2018-11-13
First posted
2018-09-10
Last updated
2023-07-12
Results posted
2023-07-12

Locations

1 site across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT03664011. Inclusion in this directory is not an endorsement.