NCT03663517

Gestational Age Specific Thyroid Function Reference Range

Gestational Age Specific Thyroid Function Reference Range in Hong Kong

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 599 (actual)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: Female
• Age: 16 Years – 50 Years
• Healthy volunteers: Accepted

Summary

It has been well accepted that maternal thyroid dysfunction has adverse affects on both mothers and fetuses. However, the dramatical changes during pregnancy make the interpretation of thyroid function test (TFT, i.e. free triiodothyronine \[FT3\], free thyroxine \[FT4\] and thyrotropin \[TSH\]) very difficult. Previous studies have shown that the level of thyroid hormones differs from non-pregnant population and varies from gestational ages. Moreover, studies have shown the agreement among different instrument platforms was quite low. This study is aimed to determine gestational age specific TFT reference ranges of the local pregnant population for all available platforms currently used under Hospital Authority and Department of Health.

Conditions

• Thyroid
• Reference Values
• Pregnancy

Timeline

• Start date: 2014-07-02
• Primary completion: 2016-04-30
• Completion: 2016-04-30
• First posted: 2018-09-10
• Last updated: 2018-09-10