NCT03662113

Effect of Domperidone on Completion Rate of Vedio Capsule Endoscopy

Effect of Domperidone on Completion Rate of Vedio Capsule Endoscopy: a Prospective Randomized Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Children's Hospital of Fudan University · Academic / Other
• Sex: All
• Age: 3 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

Video capsule endoscopy (VCE) has become an established technique to investigate the presence of small bowel pathology. But the limited battery life of capsules can lead to incomplete small bowel visualization. There is a rationale to use prokinetic agents prior to VCE reduce the chances of an incomplete small bowel examination via decrease gastric transit time (GTT). Investigators are aimed to prospectively compare the completion rate of VCE in pediatric patients receiving prokinetic with those receiving no prokinetic.

Detailed description

Eligible children were randomly divided into two groups: domperidone prior to VCE and water prior to VCE. The primary outcome measure was the completion rate. Secondary outcome measures included the GTT and SBTT.

Conditions

• Capsule Endoscopy
• Pediatric Disorder

Interventions

Type	Name	Description
DRUG	Domperidone	5ml Domperidone prior to VCE
DIETARY_SUPPLEMENT	water	5ml water prior to VCE

Timeline

• Start date: 2017-11-01
• Primary completion: 2018-11-01
• Completion: 2018-11-01
• First posted: 2018-09-07
• Last updated: 2018-12-17

Locations

1 site across 1 country: China