NCT03661749

Urinary Protein to Creatinine Ratio in Term Pregnant Women

Urinary Protein to Creatinine Ratio in Term Pregnant Women: What is the Effect of a Clean Catch Urine

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 240 (estimated)
• Sponsor: St. Luke's Hospital, Pennsylvania · Academic / Other
• Sex: Female
• Age: 16 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

This study will determine the incidence of elevated U Pr/Cr in normal term pregnant women. In addition we will determine if a "clean catch" urine has an effect on the U Pr/Cr.

Detailed description

Clean catch urine should be used due to possible vaginal secretion contamination with falsely elevated U Pr/Cr ratio. However, no supporting reference was found in the article and no control group with random urine collection for comparison to clean catch specimen U Pr/Cr was included in their study. The original studies that validated spot Pr/Cr urine as a predictor of 24 -hour total urine protein used random non-clean catch random urines . They had an r value of .93-.99 in estimating total protein excreted in 24 hours. At our institution we use Siemens-base test to determine U Pr/Cr. In the product insert the company states that no special patient preparation is necessary. Thus, this study will determine the incidence of elevated U Pr/Cr in normal term pregnant women. In addition we will determine if a "clean catch" urine has an effect on the U Pr/Cr.

Conditions

• Pregnancy Complications

Interventions

Type	Name	Description
OTHER	clean catch	clean catch technique applied to collect urine for PR/CR ratio

Timeline

• Start date: 2018-09-01
• Primary completion: 2019-08-01
• Completion: 2019-11-01
• First posted: 2018-09-07
• Last updated: 2018-09-07

Locations

1 site across 1 country: United States