NCT03660891

OS NMB Depth Measured by Central and Peripheral Monitor.

Observational Study Measuring Neuromuscular Block Depth by a TOF or PTC Monitor on the Thumb and on the Upper Arm of the Same Side.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 20 (estimated)
• Sponsor: AZ Sint-Jan AV · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Comparing during anesthesia in the same patient 2 neuromuscular monitors on the same arm.

Detailed description

NMT (neuromuscular transmission) depth can be measured at the same arm with two different methods during clinical practice. the first (TOF Watch) measures the musculus adductor pollicis acceleration while the second method (TOF Cuff Monitor) uses a blood pressure cuff to measure the pressure changes induced by the upper arm muscles. During general anesthesia when NMB (neuromuscular block) is required both methods are used. Every 5 minutes, if clinical required, the NMB is monitored by TOF-PTC. If the measurement of TOF is zero the monitor continues by measuring PTC ( the system will measure TOF followed by PTC if TOF is zero) TOF-PTC is recorded and later compared for identity or systematic difference in one or the other direction. The measured answer can be TOF 4 (4 answers) with a ratio between answer 1 and 4 expressed and a percentage, TOF 3 (3 answers), TOF 2, TOF 1, TOF 0 + PTC 20, TOF 0 + PTC 19, up to TOF 0 + PTC 0

Conditions

• Neuromuscular Blockade

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	measuring neuromuscular block	During anesthesia patients are monitored with two instead of one NMT monitor. the difference in measured TOF-PTC is compared

Timeline

• Start date: 2020-08-01
• Primary completion: 2020-12-30
• Completion: 2021-12-31
• First posted: 2018-09-07
• Last updated: 2020-03-23

Locations

1 site across 1 country: Belgium