NCT03660306

Impact of OFA During LPV on Postoperative Oxygen Saturation

Observational Study Evaluating the Impact of Opioid Free Anesthesia During Lung Protective Ventilation on Postoperative Oxygen Saturation.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 64 (actual)
• Sponsor: AZ Sint-Jan AV · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Opioids used intra operative increase the amount of opioids needed post operative to control post operative pain. if opioids are given post operative, we assume that more atelectasis and hypoxia takes place even after lung protective ventilation. These postoperative lower oxygen saturations will require giving more frequent oxygen therapy.

Detailed description

This is an observational study where the attending anesthesiologist decides to use opioid free or opioid general anesthesia based on his/her expertise. Every patient gets a lung protective ventilation and emergence from anesthesia using the principles set forward in the consensus meeting by Young C BJA 2019. A lung recruitment followed by high PEEP is given when lung compliance decreases below 40 ML/cmH20. The lowest oxygen saturation without adding oxygen therapy is noted post extubation at moment of admission in PACU, after having given an opioid as analgesic and at moment of discharge from PACU.. If post operative satuation drops below 94% oxygen therapy is given and noted.

Conditions

• Decreased Lung Compliance
• Oxygen Requirement

Interventions

Type	Name	Description
PROCEDURE	opioid anesthesia	opioid anesthesia means using sufentanil during surgery
PROCEDURE	opioid free anesthesia	opioid free anesthesia means giving no opioids during surgery

Timeline

• Start date: 2018-08-01
• Primary completion: 2019-10-31
• Completion: 2019-11-05
• First posted: 2018-09-06
• Last updated: 2019-12-03

Locations

1 site across 1 country: Belgium