Trials / Completed
CompletedNCT03659812
Magnetic Activated Cell Sorting in Artificial Insemination With Donor Sperm
Application of Magnetic Activated Cell Sorting (MACS) of Spermatozoa in Artificial Insemination Cycles With Donor Sperm (AID)
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 130 (actual)
- Sponsor
- Vida Recoletas Sevilla · Academic / Other
- Sex
- Female
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is to analyse the efficacy of MACS technique for the selection of spermatozoa and its effects on implantation, pregnancy and miscarriage rate. This study will be performed by two IVI clinics (IVI Sevilla and IVI Madrid) with the purpose of finding new techniques that allow us to better select spermatozoa and improve the results of assisted reproduction techniques.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | MACS technique | MACS is a technique that allow us to tag and detect apoptotic spermatozoa. These apoptotic spermatozoa have phosphatidylserine in their membranes, so we add magnetic beads with Annexin V, which binds specifically to phosphatidylserine. The spermatozoa are then tagged and can be retained in a magnetic field, allowing us to collect just the non-apoptotic spermatozoa. |
Timeline
- Start date
- 2017-11-07
- Primary completion
- 2018-02-16
- Completion
- 2018-04-13
- First posted
- 2018-09-06
- Last updated
- 2018-09-06
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT03659812. Inclusion in this directory is not an endorsement.