Trials / Completed
CompletedNCT03654781
Impact of Periodontal Treatment on Gastric Helicobacter Pylori Eradication
Periodontal Tedavinin Helikobakter Pilori Eradikasyon ve Rekürrensine Katkısının İncelenmesi
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 98 (actual)
- Sponsor
- Ondokuz Mayıs University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The efficacy of conventional systemic antibiotic therapy for eradication of gastric H. pylori has been seriously challenged by antibiotic resistance. Identification of alternative therapeutic strategies might help to overcome the limitation. The investigators' aim was to examine the effect of adjunct periodontal therapy, on gastric H. pylori eradication rate.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Triple therapy | triple therapy:a 10-day course of a Lansoprazole (proton pump inhibitor )combined with amoxicillin (2 × 1 g daily) and clarithromycin (2 × 500 mg daily).(trio) |
| PROCEDURE | professional periodontal treatment | periodontal treatment consisting of mechanical periodontal treatment (scaling and root planing) Oral hygiene insruction Periodontal treatment started concurrently with triple therapy |
Timeline
- Start date
- 2008-04-21
- Primary completion
- 2011-07-07
- Completion
- 2012-02-17
- First posted
- 2018-08-31
- Last updated
- 2018-08-31
Source: ClinicalTrials.gov record NCT03654781. Inclusion in this directory is not an endorsement.