NCT03653143

JASPER Intervention in Down Syndrome

Pilot Study of JASPER in Down Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Boston Children's Hospital · Academic / Other
• Sex: All
• Age: 24 Months – 48 Months
• Healthy volunteers: Not accepted

Summary

The goal of this study is to determine whether JASPER (Joint Attention, Symbolic Play, Engagement, Regulation), which is an intensive, targeted early behavioral intervention focused on a developmentally based approach for teaching joint engagement, joint attention, and play skills can improve behavioral / emotional regulation, social communication skills, and developmental trajectories in Down syndrome (DS). The investigators will also explore the potential use of EEG and event-related potentials (ERP) as outcome measures, as this approach may help elucidate mechanisms of change in behavior and development, and may help explain differences in development of social communication skills in individuals with DS. EEG and ERP measure may also help to predict treatment outcome.

Conditions

• Down Syndrome, Trisomy 21

Interventions

Type	Name	Description
BEHAVIORAL	JASPER	JASPER is a therapist and parent-mediated intervention that (1) targets the foundations of social communication, (2) uses naturalistic behavioral strategies to increase the rate and complexity of social communication and (3) includes parents as implementers of the intervention to promote generalization across settings and to ensure maintenance. This intervention is individualized and centered around two key developmental domains critical for social communication function: joint engagement and joint attention.

Timeline

• Start date: 2018-12-01
• Primary completion: 2021-07-31
• Completion: 2021-07-31
• First posted: 2018-08-31
• Last updated: 2022-01-18

Locations

1 site across 1 country: United States