Clinical Trials Directory

Trials / Completed

CompletedNCT03651882

Oxytocin i.m./i.v. Versus Carbetocin i.v. in Elective Cesarean Sections

Intramyometrial and Intravenous Oxytocin Compared to Intravenous Carbetocin for Prevention of Postpartum Hemorrhage in Elective Cesarean Sections - a Monocentric Randomized Controlled Study

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
550 (actual)
Sponsor
University of Zurich · Academic / Other
Sex
Female
Age
18 Years
Healthy volunteers
Accepted

Summary

Objective is to proof non-inferiority of intramyometrial and intravenous oxytocin application compared to intravenous carbetocin for prevention of postpartum hemorrhage in planned, uncomplicated cesarean deliveries.

Conditions

Interventions

TypeNameDescription
DRUGOxytocinOxytocin given in a combined regimen: after delivery 10 IE of oxytocin are applied intramyometrially and 10 IE of oxytocin are given over an infusion of 1000ml of 0.9% NaCL over 12 hours intravenously.
DRUGCarbetocinCarbetocin is given 0.1mg intravenously as a bolus after delivery.

Timeline

Start date
2018-08-07
Primary completion
2022-01-10
Completion
2022-01-10
First posted
2018-08-29
Last updated
2023-05-24

Locations

1 site across 1 country: Switzerland

Source: ClinicalTrials.gov record NCT03651882. Inclusion in this directory is not an endorsement.