NCT03651596

Leveraging mHealth Messaging to Promote Adherence in Teens With CKD

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 11 Years – 21 Years
• Healthy volunteers: Not accepted

Summary

The overall goal of this study is to develop and test effectively framed mobile health (mHealth) messages to promote medication adherence in teens with chronic kidney disease (CKD).

Detailed description

Hypertension is a risk factor for chronic kidney disease (CKD) progression. Only 77% of adolescents with CKD are adherent to antihypertensive medications despite evidence that adherence slows disease progression. Mobile health (mHealth) applications show promise for improving adherence but most are not designed within health-promotion frameworks, only send medication reminders, use unreliable outcome measures, and/or have small effects on adherence. Nonadherence is a public health problem that may benefit from using health communication strategies to advance beyond reminders and improve mHealth efficacy. Highly effective health messages modify perceptions, attitudes, and skills to facilitate behavioral change; inappropriately framed messages (e.g., use of fear appeals) may have unintended, negative effects on health behaviors (i.e., reduce adherence). For adolescents with CKD, framing mHealth messages to motivate adherence may be a key factor in preventing disease progression; however, there has been little research to guide the use of this approach. Hence, the current study aims to develop and test effectively framed mobile health (mHealth) messages to promote medication adherence in teens with CKD. Prior to study recruitment, the intervention messages will be developed by the research team and key stakeholders before testing in this pilot randomized controlled trial (RCT). Adolescents/young adults with CKD will be invited to participate in the pilot RCT to evaluate the intervention messages versus an active control condition; the primary outcome is antihypertensive medication adherence and secondary outcomes are participants' responses to surveys.

Conditions

• Chronic Kidney Diseases
• Adherence, Medication
• Communication

Interventions

Type	Name	Description
BEHAVIORAL	mHealth Messaging Intervention Group	The newly developed intervention messages will be sent to individuals assigned to the intervention group during the study.
BEHAVIORAL	Standard mHealth Messaging Group	Standard mHealth messages will be sent to individuals assigned to the active control group during the study.

Timeline

• Start date: 2018-10-01
• Primary completion: 2020-01-14
• Completion: 2020-01-14
• First posted: 2018-08-29
• Last updated: 2020-04-09

Locations

1 site across 1 country: United States