NCT03649308

Negative Pressure Wound Therapy Compared to Traditional Care After Skin Grafting

Negative Pressure Wound Therapy Compared to Traditional Care After Split-thickness Skin Grafting - a Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (estimated)
• Sponsor: Central Finland Hospital District · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare negative pressure wound therapy to traditional care after split-thickness skin grafting in patients aged over 18.

Detailed description

Split-thickness skin grafting (STSG) is one of the most commonly used techniques in reconstructive plastic surgery and dermatology. Skin grafts are being used to cover skin defects caused by multiple etiologies. Traditionally, patients are immobilized in bed or in wheelchair for up to five days after surgery. Long immobilization decreases patients overall ability to function and increases the length of the stay in hospital. Negative pressure wound therapy (NPWT) have been used successfully in treatment of acute, chronic and diabetic ulcers. It is proposed that NPWT increases capillary blood flow, decreases bacterial contamination, seroma formation and swelling. Using NPWT on split-thickness skin grafts after burns is well documented. It increases skin graft take ratio and speeds up healing. Aim of this study is to compare NPWT to traditional treatment after STSG for any indication in patients aged 18 to 99. This is a two-arm, multicenter, randomized prospective trial with 160 patients.

Conditions

• Wound of Skin
• Wound Heal
• Wound
• Wound Open
• Wound Breakdown
• Skin Wound
• Skin Scarring

Interventions

Type	Name	Description
DEVICE	Negative Pressure Wound Therapy	An immediate mobilization and negative pressure wound therapy (PICO) initiated after surgery.
PROCEDURE	Conventional treatment	Traditional treatment with conventional wound dressing and 5 days of immobilization after surgery.

Timeline

• Start date: 2018-09-19
• Primary completion: 2024-12-31
• Completion: 2025-12-31
• First posted: 2018-08-28
• Last updated: 2024-02-13

Locations

2 sites across 1 country: Finland