NCT03649269

PC-300 Tea Effect on Triglyceride Levels

Eryngium Heterophyllum + Amphipterygium Adstringens Tea Effect on Triglyceride Levels

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: Ciprés Grupo Médico CGM SC · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Herbal medicine represents an alternative for treating dyslipidemia. The aim of this project was to evaluate the PC-300 tea (Eryngium heterophyllum egelm + Amphipterygium adstringens) against hypertriglyceridemia. Baseline samples of serum total cholesterol and triglycerides were obtained and measured again after 1 month of treatment with the following two alternatives: 1) PC-300, one cup half an hour before eating, and 2) bezafibrate 200 mg/d.

Detailed description

It was a descriptive, prospective, longitudinal, and comparative clinical study developed at Ciprés Grupo Médico S.C. (CGM), Toluca, Mexico, from January 2014 to December 2014. Patients with hypertriglyceridemia were invited to participate in the study. Voluntary subjects were assigned sequentially into two treatment groups: 1) fibrate (bezafibrate) 200 mg/day, and 2) PC-300 tea, one cup half an hour before eating. Patients were measured (m) and weighed (kg) (Obi, México). Body mass index (BMI) was calculated as weight (kg) divided by height (m) squared. Blood pressure was measured with a calibrated sphygmomanometer (Welch Allyn, USA) after 5 min of rest. All of the patients were given a low lipid diet. Calculated kcal were based on ideal weight minus 200 kcal/day if overweight. Results were expressed as mean ± Standard deviation (SD). Differences between initial vs. final values were compared with the Mann-Whitney U test. The normality hypothesis was tested using the Kolmogorov-Smirnov test. A p value of \<0.05 was considered significant. All tests were performed with the SPSS ver. 23 statistical software program.

Conditions

• Hypertriglyceridemia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	PC-300 tea.	Patients had to drink one cup of the tea half an hour before breakfast, main meal and dinner.
DRUG	Bezafibrate	Patients were prescribed 200 mg/day at night.

Timeline

• Start date: 2014-01-01
• Primary completion: 2014-11-30
• Completion: 2014-12-31
• First posted: 2018-08-28
• Last updated: 2018-08-28