Trials / Unknown
UnknownNCT03648736
Time Course of Circulating Myocardial Biomarkers After a TASH Procedure.
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (estimated)
- Sponsor
- RWTH Aachen University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The study evaluates the released myocardial substances in blood of HOCM patients after TASH procedure (small "controlled" myocardial infarction). This helps to identify new pathomechanisms and biomarker and thus provides a better understanding of development and progress of cardiac insufficiency.
Detailed description
All patients who receive a TASH procedure in the Medical Clinic I routinely receive routinely implementation of arterial pressure catheter for invasive blood pressure monitoring (usually Arteria radialis) as well as a central venous catheter. Directly after the procedure, the blood is taken through the central venous catheter. The operation is then terminated as planned. The postoperative treatment is performed according to the Standard Operating Procedures (SOPs) of the Medical clinic I -regular blood sampling is performed to monitor the patient's cardiac, renal and hepatic lab values. The patient is released on the 3-5th post-operative day. As part of a routine outpatient visit to the Medical Clinic I 1 week and 1 month after the TASH procedure, an anamnestic record as well as a blood analysis is made. One month after the TASH procedure, an echocardiographic follow-up of the HOCM is routinely performed. Adverse events or serious adverse events are documented, assessed and reported in accordance with GCP (good clinical practice).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | blood withdrawal | * peripheral-venous before TASH, day 1, 2, 3, one week and one month after TASH procedure * central-venous during TASH |
Timeline
- Start date
- 2018-10-10
- Primary completion
- 2021-05-01
- Completion
- 2021-05-01
- First posted
- 2018-08-27
- Last updated
- 2020-03-12
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT03648736. Inclusion in this directory is not an endorsement.