NCT03648411

Drug Resistance Among Asymptomatic Infection

Assessment of Drug Resistance Molecular Markers in Asymptomatic Malaria Among Migrant Workers in Myanmar

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 765 (actual)
• Sponsor: Department of Medical Research, Lower Myanmar · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

A cross-sectional study will be conducted in selected 2 sentinel sites for assessment of drug resistance falciparum and vivax among asymptomatic infection in migrant workers in Myanmar.

Detailed description

Although malaria prevalence is decreasing in Myanmar, drug resistance threatens the malaria elimination by 2030 especially high risk persons including migrant population. Previous study indicated that asymptomatic malaria parasite carried drug resistance gene such as K13 mutant that is genetically responsible for artemisinin resistant falciparum malaria. These asymptomatic carries may be a source to spread the disease and it is very important to conduct the surveillance on drug resistance status among high vulnerable persons. Unfortunately, there is no study to assess the drug resistance molecular markers in asymptomatic malaria among migrant workers in Myanmar. Therefore, this study fulfills the gaps of knowledge on important of asymptomatic hidden infection exploring to formulate the recommendation for elimination of malaria in Myanmar. In this study, asymptomatic infections are screened by rapid diagnostic test, microscopy and molecular methods.

Conditions

• Drug Resistant Malaria
• Asymptomatic Infections
• Migrant Workers

Interventions

Type	Name	Description
GENETIC	Drug resistance molecular markers	Proportion of the drug resistance molecular markers will be found-out and compared.

Timeline

• Start date: 2019-01-12
• Primary completion: 2019-12-30
• Completion: 2020-05-20
• First posted: 2018-08-27
• Last updated: 2020-07-22

Locations

1 site across 1 country: Burma