NCT03647059

Rapid Assessment of Donor Liver Quality

Real-time Noninvasive Assessment of Donor Liver Quality

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Aims： 1. Conduct multi-center, prospective and open research on liver quality assessment and establish LSCM liver quality assessment system 2. Classification of liver quality grades by LSCM for different pathological conditions (steatosis, fibrosis, hepatocyte necrosis, etc.) 3. Compare the specificity and sensitivity of LSCM evaluation results with the results of liver donor quality evaluation and intraoperative pathological biopsy results. 4. LSCM classifies the quality of donor liver and compares the recovery of liver function on the first day after liver transplantation. 5. LSCM grades the quality of donor liver and compares the long-term prognosis

Conditions

• Transplant; Failure, Liver

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	LSCM examination	Cut a piece of donor liver and conduct the LSCM examination after staining fluorescein

Timeline

• Start date: 2018-08-15
• Primary completion: 2020-08-15
• Completion: 2022-08-15
• First posted: 2018-08-27
• Last updated: 2018-08-27

Locations

1 site across 1 country: China