NCT03646851

Aspergillus and Chronic Obstructive Pulmonary Disease Evolution

Impact of Aspergillus on Chronic Obstructive Pulmonary Disease Evolution

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective multicenter cohort study which includes all consecutive COPD patients who come for a visit in one the participating pneumologist. They will have to do a sputum and to complete some questionnaries. Questionnaries will be redone by phone after 1 and 3 months and during the visit after 6 months. We will correlate aspergillus presence in sputum with quality of life (QoL), and COPD symptoms evaluated by questionnaires.

Detailed description

Aspergillosis disease is a growing problem. These diseases are not yet uncommon in chronic obstructive pulmonary disease patients. (COPD). Aspergillosis disease are very difficult to be diagnosed or treated. Isolation of aspergillus in sputum of patients is not always responsible of a real disease. Need of treatment is discussed. That is why, we will conduct a prospective cohort study to evaluate aspergillus rate in respiratory samples of COPD patients (GOLD stage III or IV)

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Questionnaries	patients will have to do a sputum and to complete some questionnaries

Timeline

• Start date: 2018-03-15
• Primary completion: 2019-03-15
• Completion: 2019-03-15
• First posted: 2018-08-24
• Last updated: 2025-11-19

Locations

4 sites across 1 country: France