Trials / Completed
CompletedNCT03646773
Microvascular Effects of Intravenous Esmolol During Postoperative Atrial Fibrillation
Microvascular Effects of Intravenous Esmolol in Patients With Normal Cardiac Function Undergoing Postoperative Atrial Fibrillation: a Prospective Pilot Study in Cardiothoracic Surgery
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 25 (actual)
- Sponsor
- Hospices Civils de Lyon · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Background: Postoperative atrial fibrillation (POAF) is commonplace after cardiothoracic surgery. A rate control strategy by using short-acting beta blockers is recommended as a first-line therapy in patients without hemodynamic instability. Microcirculatory effects of POAF and esmolol have not been yet investigated. The investigators made the hypothesis that POAF without hemodynamic instability would induce microvascular dysfunction which could be reversed by intravenous esmolol.
Conditions
Timeline
- Start date
- 2015-12-01
- Primary completion
- 2016-09-01
- Completion
- 2016-11-01
- First posted
- 2018-08-24
- Last updated
- 2018-08-24
Source: ClinicalTrials.gov record NCT03646773. Inclusion in this directory is not an endorsement.