Trials / Completed
CompletedNCT03644979
Skydiving as a Model of Psychological Stress and Its Effect on Intestinal Barrier Function
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Örebro University, Sweden · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
In this study, it will be investigated how psychological stress evoked by skydiving affects the intestinal permeability in 20 healthy subjects. Participants attend two visits: 1) Skydiving visit, 2) Negative control visit. At all visits, saliva samples, blood samples, and faecal samples are collected, and the multi-sugar permeability test is performed. In this test, participants drink a sugar solution and then collect urine for 5 and 24 h. The ratio of the sugars detected in the urine is a reflection of the intestinal permeability. Saliva samples are collected for assessment of cortisol, a stress marker. Blood and faecal samples are collected for assessment of markers of intestinal barrier function and inflammation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Skydiving | Tandem skydiving (with an experienced instructor) |
Timeline
- Start date
- 2018-07-01
- Primary completion
- 2018-10-31
- Completion
- 2018-10-31
- First posted
- 2018-08-23
- Last updated
- 2019-01-03
Locations
1 site across 1 country: Sweden
Source: ClinicalTrials.gov record NCT03644979. Inclusion in this directory is not an endorsement.