Trials / Completed
CompletedNCT03640741
Changes in Cerebral Oxygenation Studies During Laparoscopy Procedure
Changes in Cerebral Oxygenation Studies Carried Out With the Use of Non-invasive Time-resolved Near-infrared Spectroscopy Device in Patients Undergoing Laparoscopy Procedure
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 17 (actual)
- Sponsor
- Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The motivation results from the fact, that an intra-abdominal pressure is correlated with cerebral perfusion, in a mechanism of reducing venous outflow. Moreover, elevated intra-abdominal pressure leads to increase in intracranial pressure and decrease of cerebral perfusion pressure. The main aim of the study was to investigate an influence of increase in intra-abdominal pressure on cerebral oxygenation measured with the use of non-invasive optical technique.
Detailed description
The investigators applied time resolved near infrared spectroscopy device in order to estimate changes in hemoglobin concentration in a brain during gynecological procedure that involves laparoscopy. The optodes were positioned on a forehead on left and right hemisphere. The measurements were carried out during whole medical procedure, including anesthesia, start and stop of insufflation of abdominal cavity with carbon dioxide (CO2), surgical procedure, release of CO2 and waking up a patient. In those studies the special emphasis was put on a period of insufflation of abdominal cavity with CO2.
Conditions
- Increase in Intra-abdominal Pressure
- Increase in Intracranial Pressure (ICP)
- Laparoscopy
- Cerebral Perfusion and Oxygenation
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Laparoscopy | The studies are carried out on patients who undergoes gynecological procedure that involves laparoscopy. |
Timeline
- Start date
- 2016-07-11
- Primary completion
- 2016-07-25
- Completion
- 2017-12-18
- First posted
- 2018-08-21
- Last updated
- 2018-08-21
Source: ClinicalTrials.gov record NCT03640741. Inclusion in this directory is not an endorsement.