NCT03638973

Comparison of Sample Biopsy Using Scalpel or Er:YAG Laser

Randomized Prospective Study for the Comparison of Sample Biopsy Using Scalpel or Er:YAG Laser

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 44 (estimated)
• Sponsor: University of Zurich · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Accepted

Summary

For certain changes in the oral mucosa a histopathological examination of the affected tissue is indicated to confirm the diagnosis. The gold standard is the biopsy by scalpel. The aim of this study is to compare the alternative method of tissue sampling using the erbium doped yttrium aluminium garnet (Er:YAG) laser with the gold Standard.

Detailed description

Various parameters are compared, such as the pain intensity during and after the biopsy, the evaluation of the tissue removed by the histopathologist, the occurrence of bleeding during and after the removal and the time required for both therapies. Patients who agree to participate in the study will be randomized (randomly) to either therapy.

Conditions

• Laser Burn
• Gingival Disease
• Biopsy Wound

Interventions

Type	Name	Description
PROCEDURE	Biopsy	Removal of specimen biopsies in patients with leukoplakic or lichenoid mucosal lesions using Er: YAG laser or scalpel under previous local anesthesia.

Timeline

• Start date: 2018-11-01
• Primary completion: 2019-11-01
• Completion: 2020-11-01
• First posted: 2018-08-20
• Last updated: 2018-10-12

Locations

1 site across 1 country: Switzerland