NCT03638804

89Zr-KN035 PET Imaging in Patients With Advanced Solid Tumors

89Zr-labeled KN035 PET Imaging in Patients With PD-L1positive Advanced Solid Tumors

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: The First Affiliated Hospital of Soochow University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This is a single arm study by using 89Zr-labeled KN035 (89Zr-KN035) PET imaging to evaluate the biodistribution and target lesion uptake of 89Zr-KN035 in patients with PD-L1 positive advanced solid tumors.

Detailed description

The overall purpose of the study is to evaluate the biodistribution and target lesion uptake of 89Zr-KN035 in patients with PD-L1 positive advanced solid tumors by using PET imaging. Safety will be observed after 89Zr-KN035 injection, and radiation dosimetry of 89Zr-KN035 will be calculated.

Conditions

• Solid Tumor, Adult

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	89Zr-KN035	Single injection of 89Zr labeled KN035 in subjects to observe KN035 affinity in PD-L1 expressed Solid tumors by using PET imaging.

Timeline

• Start date: 2018-11-12
• Primary completion: 2019-12-01
• Completion: 2019-12-01
• First posted: 2018-08-20
• Last updated: 2018-12-05

Locations

1 site across 1 country: China