Trials / Completed
CompletedNCT03636971
Gait Analysis Following Knee Viscosupplementation
Gait Analysis Following Single-shot Hyaluronic Acid Supplementation: a Pilot Randomised Double-blinded Clinical Trial
- Status
- Completed
- Phase
- Phase 2 / Phase 3
- Study type
- Interventional
- Enrollment
- 22 (actual)
- Sponsor
- Brigitte Jolles, MD · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is a pilot, double-blind, randomised trial that investigates which gait parameters are more sensitive following a single bolus injection of hyaluronic acid with mannitol, hyaluronic acid with sorbitol, or saline placebo for knee osteoarthritis. Outcome measures are gait analysis through a inertial sensors (Physilog), Knee Society Score (KSS), University of California Los Angeles (UCLA) activity-scale and EuroQol 5Dimensions. Follow-up will be of 4 weeks.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | hyaluronic acid with mannitol | single shot injection (Ostenil Plus®, TRB Chemedica SA, CH, 1800kD) |
| DRUG | hyaluronic acid with sorbitol | single shot injection (Synolis®, Gebro-Pharma AG, CH, 2000 kD) |
| DRUG | Placebos | single shot injection of saline, same volume |
Timeline
- Start date
- 2013-05-01
- Primary completion
- 2015-12-30
- Completion
- 2017-01-01
- First posted
- 2018-08-17
- Last updated
- 2018-08-17
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT03636971. Inclusion in this directory is not an endorsement.