NCT03636139

Cognitive Control of Negative Stimuli in BPD

Effects of Transcranial Direct Current Stimulation on the Cognitive Control of Negative Stimuli in Borderline Personality Disorder

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Freie Universität Berlin · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Borderline personality disorder (BPD) is characterized by impairments in the cognitive control of negative information. These impairments in cognitive control are presumably due to blunted activity of the dorsolateral prefrontal cortex (dlPFC) along with enhanced activations of the limbic system. However, the impact of an excitatory stimulation of the dlPFC still needs to be elucidated. In the present study, we therefore assigned 50 patients with BPD and 50 healthy controls to receive either anodal or sham stimulation of the right dlPFC in a double-blind, randomized, between-subjects design.

Conditions

• Borderline Personality Disorder

Interventions

Type	Name	Description
DEVICE	transcranial DC stimulation : anodal	anodal stimulation of the right dlPFC (i.e. F4) for 20 minutes
DEVICE	transcranial DC stimulation : sham	sham stimulation of the right dlPFC (i.e. F4) for 20 minutes

Timeline

• Start date: 2016-01-01
• Primary completion: 2017-06-01
• Completion: 2017-06-01
• First posted: 2018-08-17
• Last updated: 2024-02-22