NCT03635671

Diabetic Retinopathy and Subclinical Signs of Disease Transition

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 5 (actual)
• Sponsor: University of British Columbia · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The prevalence of diabetes mellitus (DM) is increasing worldwide. Diabetic retinopathy is the most prevalent complication of DM and a leading cause of visual impairment. Some factors are known to temporarily aggravate or improve diabetic retinopathy, but underlying pathophysiologic factors are still unknown. High-resolution imaging techniques of the retina and its supplying vascular networks now allow novel insight to subtle changes that cannot be appreciated in standard fundus examination. In detail, the investigators image study patients with optical coherence tomography (OCT) - technology, that provides morphological information of retinal structure and the supplying vessels in a non-invasive way. Retinal layer thickness as well as capillary density will be quantified and followed in patients that are in a critical period of disease transition to better understand the process of diabetic retinopathy.

Conditions

• Diabetic Retinopathy

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Optical Coherence Tomography Angiography	Retinal scans will be acquired at each follow up visit

Timeline

• Start date: 2018-09-01
• Primary completion: 2019-07-15
• Completion: 2019-07-15
• First posted: 2018-08-17
• Last updated: 2019-08-29

Locations

1 site across 1 country: Canada