NCT03634787

Heat Shock Proteins: a Pathogenic Driver and Potential Therapeutic Target in Acute Pancreatitis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 280 (estimated)
• Sponsor: Vilnius University · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: —

Summary

To investigate the role of Heat Shock Proteins in the mechanism of acute severe pancreatitis. In addition to test the potential treatment target of acute pancreatitis. All patients who present with clinical symptoms of acute pancreatitis are evaluated for the enrollment of the study.

Detailed description

All patients with acute pancreatitis are evaluated according to modified Atlanta classification acute pancreatitis severity scores. Blood serum, urine and DNA samples are collected from all patients presented on admission, after 24 hours, 48 hours, 72 hours. CT is performed in al patients to evaluate necrosis of pancreas Day 5-7 since hospital admission. If necrosis is not present follow-up is stopped.

Conditions

• Acute Pancreatitis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	CT Scan Day 5-7	Computed Tomography on Day 5-7 according to a clinical protocol.

Timeline

• Start date: 2017-10-20
• Primary completion: 2021-12-01
• Completion: 2021-12-30
• First posted: 2018-08-16
• Last updated: 2018-08-16

Locations

1 site across 1 country: Lithuania