Trials / Unknown
UnknownNCT03633981
Multimodal Assessment of the Neurological Prognosis of Patients With Brain Lesions on ExtraCorporeal Life Support
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- Centre Hospitalier Universitaire Dijon · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
It seems of the greatest importance to evaluate the neurological prognosis of patients with brain lesions after cardiorespiratory arrest or circulatory failure requiring circulatory assistance. However, to date, there is no clinical or paraclinical diagnostic test to reliably assess the future of these patients. The objective of this study is to highlight the clinical and imaging factors for establishing a neurological prognosis in patients at risk of brain lesions under ExtraCorporeal Life Support (ECLS).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | clinical examinations | Collection of data from the following tests at H0 (as soon as the ECLS is put in place), H12 (within 12 hours following stabilisation of the dynamic state), H24 and every day until complete neurological recovery: * right and left pupillometry (3 times) * BIS values * right and left NIRS values * right and left transcranial Doppler * neurological clinical examination |
| OTHER | neurological assessment when a neurological event occurs | next neurological event: * seizures * pupillary asymmetry * myoclonias * brain stem reflex abnormalities * osteotendinous reflex abnormalities |
| OTHER | mortality assessment | to 28 days |
Timeline
- Start date
- 2018-09-01
- Primary completion
- 2019-09-01
- Completion
- 2019-12-01
- First posted
- 2018-08-16
- Last updated
- 2018-10-16
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03633981. Inclusion in this directory is not an endorsement.