NCT03633032

Radiation-free Bone Imaging UTE MRI in Healthy and Diseased Patients

Radiation-free Bone Imaging by Ultrashort Echo Time (UTE) Magnetic Resonance Tomography (MRT)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Roman Guggenberger · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

In summary, the investigators want to investigate whether UTE sequences are capable to replace imaging techniques involving ionizing radiation for bone imaging in the future. This would improve patient care greatly and might reduce medical imaging associated cancer risk drastically from an epidemiological standpoint. This field of research can be considered cutting-edge. The investigators determine this study promising to provide substantial generalizable knowledge and hope that this study results will improve patient care worldwide considerably.

Detailed description

To date, definite depiction of anatomy or pathologies of bony structures requires ionizing radiation by using radiographs or computed tomography (CT) since conventional magnetic resonance imaging (MRI) that does not require ionizing radiation cannot depict bony structures well. Modern MR techniques, collectively referred to as ultrashort time to echo (UTE) sequences, have overcome this issue by acquiring the signal data much faster and therefore are able to acquire sufficient MR signal from bony structures. The investigators want to investigate if UTE sequences are capable to depict bony anatomy and pathology similar to imaging examination techniques involving ionizing radiation. Healthy adult and minor participants, as well as adult and minor participants, referred for a clinically indicated MRI involving the skeletal system will be included.

Conditions

• Bone Anatomy
• Bone Diseases

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Acquiring of ultrashort echo time (UTE) MRI sequences	Modern MRI sequences (ultrashort echo time (UTE)) for a better depiction of bone anatomy

Timeline

• Start date: 2018-10-01
• Primary completion: 2023-12-06
• Completion: 2023-12-06
• First posted: 2018-08-16
• Last updated: 2023-12-07

Locations

1 site across 1 country: Switzerland