Trials / Completed
CompletedNCT03632915
Pharmacokinetics of Antiepileptics in Patients on CRRT
Pharmacokinetics of Antiepileptic Drugs in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 18 (actual)
- Sponsor
- University of Maryland, Baltimore · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the study is to measure levels of any of the following AEDs (levetiracetam, phenobarbital, phenytoin, ketamine, valproic acid, lacosamide) in blood and effluent on critically ill patients receiving CRRT in order to characterize drug pharmacokinetics and optimize dosing strategies in patients on CRRT.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Levetiracetam | Standard of care |
| DRUG | Lacosamide | Standard of care |
| DRUG | Phenytoin | Standard of care |
| DRUG | Phenobarbital | Standard of care |
| DRUG | Ketamine | Standard of care |
| DRUG | Valproic Acid | Standard of care |
Timeline
- Start date
- 2017-11-20
- Primary completion
- 2019-12-31
- Completion
- 2019-12-31
- First posted
- 2018-08-16
- Last updated
- 2021-10-05
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT03632915. Inclusion in this directory is not an endorsement.