NCT03632174

Evaluation and Comparison of 2 Cosmetic Investigational Products in Adults With Atopic Dermatitis

Clinical Study for the Evaluation and Comparison of Cutaneous Acceptability and the Efficacy of 2 Cosmetic Products, Under Normal Conditions of Use, in Adult Participants With Atopic Dermatitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: BioGaia AB · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The study consists in the application of 2 investigational products (one group per investigational product) under normal conditions of use, in adult participants with Atopic Dermatitis. It is carried out on cosmetic products, with the aim to further confirm safety of these products

Detailed description

Probiotics are live micro-organisms which when administered in adequate amounts can exert a health benefit on the host. This health-promoting effects of Lactobacillus reuteri have been extensively studied in the gastrointestinal tract but it is clear that other areas are also interesting for the use of probiotics. Atopic Dermatitis is a relapsing inflammatory skin disease appearing on persons with a genetic predisposition of allergic pathology. AD generally starts in childhood, however in some cases can continue into adult hood, in at least 10% of cases. AD can effect a persons quality of life and in the chronic stage it can present with dry skin and lichenification. Research has shown that probiotics have an antimicrobial, anti-inflammatory and barrier function effect, and could therefore be used on subjects with Atopic Dermatitis to relieve and protect.

Conditions

• Atopic Dermatitis

Interventions

Type	Name	Description
OTHER	Topical Ointment with L. reuteri	Topical Ointment containing live Lactobacillus reuteri DSM17938 applied twice daily in dry areas of the entire body
OTHER	Topical Ointment without L. reuteri	Topical Ointment that does not contain Lactobacillus reuteri DSM17938 applied twice daily in dry areas of the entire body

Timeline

• Start date: 2019-01-21
• Primary completion: 2019-09-02
• Completion: 2019-10-16
• First posted: 2018-08-15
• Last updated: 2019-10-22

Locations

1 site across 1 country: South Africa