NCT03631394

The Effects of Dietary Nitric Oxide and Anthocyanins on Anaerobic Exercise Performance

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Loma Linda University · Academic / Other
• Sex: All
• Age: 21 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The purpose of this graduate student research study is to investigate the effects of nitrate from beetroot powder with additional anthocyanins from tart cherry on exercise performance in healthy Loma Linda University students utilizing the Wingate Anaerobic test on stationary bike.

Detailed description

A randomized controlled double-blind crossover study with a baseline and two interventions. On day 1 (baseline), all subjects will have a lactate fingerstick measurement before and after the Wingate protocol. A random subsample (1/3 of subjects) will have 10 milliliters (2 teaspoon) of blood drawn for determination of serum allantoin. Subjects will then be equipped with a pulse oximeter and a heart rate monitor after which they will perform the Wingate Anaerobic test protocol. The protocol includes: 4 minutes of warm up, 3 seconds of warm up sprint with weights, 1-minute relaxed cycling, 2-minute rest, then 10 seconds cycling without weights. This will be followed by 30 seconds sprint with weights and end with 2 minutes of relaxed cycling. A post-activity blood draw will be performed for another 10 milliliters (2 teaspoon) of blood from the same one-third of subjects previously sampled. After baseline data collection, subjects will undergo a 1-week washout (avoiding high antioxidant foods) after which they will be randomized to treatment groups. On day 9, subjects will begin supplementation with nitrate from beetroot powder with additional anthocyanins, or nitrate from beetroot powder with a placebo for 7 days. On day 15 the subject will again repeat the same procedures as day 1, followed by another week of washout. They will supplement again on day 23 and repeat the same procedure as the first intervention on day 29.

Conditions

• Exercise

Interventions

Type	Name	Description
OTHER	beetroot and anthocyanin	Beetroot and anthocyanin will be taken for 7 days during the study two hours prior to eating.
OTHER	beetroot and placebo	Beetroot and placebo will be taken for 7 days during the study two hours prior to eating.

Timeline

• Start date: 2018-09-01
• Primary completion: 2019-04-01
• Completion: 2019-04-01
• First posted: 2018-08-15
• Last updated: 2019-05-15

Locations

1 site across 1 country: United States