NCT03630458

Digestive Properties of Carbohydrate-based Foods

Investigating Digestive Properties of Carbohydrate-based Foods

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Purdue University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Gastric emptying rate, glycemic response, fermentation, and appetitive response are being assessed after consumption of traditional West African carbohydrate-based foods (pearl millet couscous, pearl millet thick porridge) and Western type carbohydrate-based foods (wheat couscous, white rice).

Detailed description

Anecdotal evidence suggests that couscous made from pearl millet (Pennisetum glaucum), hereby referred to as millet couscous, is highly satiating in populations living in the West African Sahel. Results from a previous human study conducted the investigators indicated that traditional West African foods made from pearl millet and sorghum (millet couscous, millet thick porridge, and sorghum thick porridge) exhibit markedly delayed rates of gastric emptying compared to Western foods (pasta, boiled potatoes, and white rice) in a population from Mali, Africa. The delayed gastric emptying rate of the thick porridges can be attributed at least partially to the impact of viscosity, while the cause of the delayed gastric emptying rate of the millet couscous remains unclear. The overall aim of this research is to determine why millet couscous exhibits a delayed rate of gastric emptying, while also assessing other digestive properties to gain a better understanding of the factors that could be contributing to this outcome. Therefore, gastric emptying rate, glycemic response, fermentation, and appetitive response are all being assessed for West African and Western foods in a population residing in the United States.

Conditions

• Obesity
• Diabetes Mellitus, Type 2
• Appetitive Behavior

Interventions

Type	Name	Description
OTHER	Pearl millet couscous - made in Senegal	Pearl millet couscous (made in Senegal) was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response.
OTHER	Pearl millet couscous - made in USA	Pearl millet couscous (made in USA) was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response.
OTHER	Pearl millet thick porridge	Pearl millet thick porridge was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response.
OTHER	Wheat couscous	Wheat couscous was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response.
OTHER	White rice	White rice was tested as a comparator for gastric emptying rate, glycemic response, fermentability, and appetitive response.

Timeline

• Start date: 2018-06-11
• Primary completion: 2018-07-31
• Completion: 2018-07-31
• First posted: 2018-08-14
• Last updated: 2019-08-22

Locations

1 site across 1 country: United States