NCT03629132

PRP Prevents Recurrence of Intrauterine Adhesions

Platelet-rich Plasma(PRP) Prevents Recurrence of Intrauterine Adhesions

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Yanhong Deng · Academic / Other
• Sex: Female
• Age: 20 Years – 37 Years
• Healthy volunteers: Not accepted

Summary

Effect of platelet-rich plasma (PRP) on uterine scar fibrosis, endometrial receptivity and pregnancy outcome in patients with severe intrauterine adhesions

Detailed description

1. Inclusion criteria: patients with intrauterine adhesions (AFS score \>9 points); age 21 to 40 years old, with fertility requirements. 2. Study design:prospective, randomized controlled cohort study, patients with intrauterine adhesions were randomized into two groups, the control group and the intervention group (intraoperative and postoperative 1 week postoperative PRP). The surgical procedures and postoperative medication regimens were the same. 3. Compare the biochemical pregnancy rate, clinical pregnancy rate, abortion rate and live birth rate after hysteroscopic resection in PRP group and control group, and explore the effect of PRP on pregnancy outcome after intrauterine adhesion.

Conditions

• Intrauterine Adhesion

Interventions

Type	Name	Description
PROCEDURE	Platelet-rich plasma	Platelet-rich plasma intrauterine injection
PROCEDURE	gel	Self-crosslinking sodium hyaluronate gel intrauterine injection

Timeline

• Start date: 2018-08-15
• Primary completion: 2019-08-01
• Completion: 2019-12-30
• First posted: 2018-08-14
• Last updated: 2018-08-14