NCT03627338

Medication Adherence in Patients With Liver Cirrhosis

Medikamentenadhärenz Bei Patientinnen Und Patienten Mit Leberzirrhose

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: Hannover Medical School · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: —

Summary

With this unfunded, investigator-initiated prospective, observational, explorative, single-arm and diagnostic single-centre study the investigators aim to evaluate medication adherence in patients with advanced liver cirrhosis

Detailed description

The main objective of the study is to investigate drug adherence in cirrhotic patients and to gain a better understanding of the causes of deficient adherence including evaluation for medication beliefs, satisfaction, depression, anxiety and health-related quality of life. A number of long-term medications have been approved for this group of patients in various indications and / or recommended by guidelines. However, adherence has not been adequately investigated yet. The investigators aim to focus on the following groups of ingredients / classes: * Primary and secondary antibiotic prophylaxis (e.g. Norfloxacin) * Non-selective beta-blockers (e.g. Carvedilol and Propranolol) * diuretics (Spirolactones \[e.g. Spironolacton\], loop diuretics) Methodically, this is will be investigated in particular by taking into account the patients history, standardized questionnaires and validated interviews.

Conditions

• Medication Adherence

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	questionaire, interview	questionaire, interview

Timeline

• Start date: 2018-09-01
• Primary completion: 2021-03-31
• Completion: 2021-05-31
• First posted: 2018-08-13
• Last updated: 2020-03-12

Locations

1 site across 1 country: Germany