NCT03626441

The Effect of Ginger on the Incidence of Postoperative Nausea and Vomiting

An Evaluation of the Effectiveness of a Single Dose of Preoperative Ginger on the Incidence of Postoperative Nausea and Vomiting in Patients Undergoing Elective Gynaecological Surgery

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 110 (actual)
• Sponsor: The University of The West Indies · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study evaluates the effectiveness of ginger on the incidence of postoperative nausea and vomiting in patients undergoing gynaecological surgery. Half the patients were given an oral dose of ginger preoperatively and half received placebo.

Detailed description

Postoperative nausea and vomiting (PONV) commonly complicate surgery and may lead to a prolonged length of stay in hospital, increased complication rates and decreased patient satisfaction. Gynaecological surgery is considered high risk for PONV. Ginger is a cheap, widely available and safe natural product in Jamaica and has been found to reduce the incidence of Nausea and vomiting in other clinical situations, such as in pregnancy. It is believed to act via the inhibition of serotonergic receptors.

Conditions

• Postoperative Nausea and Vomiting

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Ginger	Capsules containing 0.5g ginger powder, flavoured with non-active essence of ginger
DIETARY_SUPPLEMENT	Placebo	Two coloured capsules containing 0.5 mg of cornstarch and flavoured with non-active essence of ginger.

Timeline

• Start date: 2017-12-02
• Primary completion: 2018-06-12
• Completion: 2018-06-14
• First posted: 2018-08-13
• Last updated: 2018-08-13

Locations

1 site across 1 country: Jamaica