NCT03625440

Acute Effects of Waterpipe Smoking on Cognitive Measures and Cardiorespiratory Parameters

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 55 (actual)
• Sponsor: Rambam Health Care Campus · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Title: Acute effects of waterpipe smoking (WPS) on cognitive measures and cardiorespiratory parameters Objectives: To evaluate the acute effect of one cession of water pipe smoking on: 1. executive functions which evaluated by cognitive tests administered included the digit span subtest Wechsler Adult Intelligence Scale (WAIS)-version III hebrew battery, and the Paced Auditory Serial Addition Test (PASAT) 2. Cardiorespiratory parameters included vital signs, spirometry parameters and lung clearance index (LCI) value 3. serum carboxyhemoglobin, nicotine, and cytokines Design: Prospective study evaluating these parameters before and after 30 minutes of water pipe smoking (WPS). Sample size: 55 participants (35 study group, 20 control group) Participant selection: Adults subjects who regularly smoke water pipe. Intervention: Each subject will undergo evaluation including cognitive tests, Cardiorespiratory parameters, carboxy- hemoglobin levels, nicotine levels, serum cytokines levels. All measurements will be evaluated before and after one cession of 30 minutes water pipe smoking

Detailed description

The effect of repeated testing 30 minutes apart without water pipe smoking (WPS) was evaluated in a group of 20 volunteers (age and sex matched). Primary outcome parameter: Change in cognitive tests scores Secondary outcome parameter:Change in Cardiorespiratory parameters included vital signs, spirometry parameters and lung clearance index (LCI) value, serum carboxyhemoglobin, nicotine, and cytokines, before and after water pipe smoking

Conditions

• Waterpipe Smoking

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	The Digit span test and PASAT with waterpipe smoking	Cognitive tests at baseline and 30minutes after waterpipe smoking
DIAGNOSTIC_TEST	The Digit span test and PASAT without waterpipe smoking	The Digit span test and Paced Auditory Serial Addition Test (PASAT) at baseline and 30minutes later

Timeline

• Start date: 2016-08-01
• Primary completion: 2017-03-01
• Completion: 2017-04-01
• First posted: 2018-08-10
• Last updated: 2018-08-10

Locations

1 site across 1 country: Israel