NCT03623048

Effect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt

Effect of Propolis and Pomegranate Extract Mouthwash on Taste Alteration, Salivary pH and Antibacterial Activity in High Caries Risk Patients

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 17 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Evaluate the effect of propolis extract mouthwash and pomegranate extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients.

Detailed description

This study will be carried out to evaluate and compare the effect of propolis extract mouthwash and pomegranate (botanical name: Punica granatum) extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients. Thats by taking unstimulated saliva samples at the morning before using the mouthwash, then taking another one after using the mouthwash and finally after 7 days, to make a bacterial culture and measure the salivary pH by a digital pH meter and evaluate taste changes by a questionnaire.

Conditions

• Decay, Dental

Interventions

Type	Name	Description
OTHER	chlorhexidine	antibacterial and anti-inflammatory mouthwash
OTHER	saline	anti-inflammatory cleansing mouthwash
OTHER	Propolis extract	antibacterial mouthwash
OTHER	pomegranate extract	antibacterial mouthwash

Timeline

• Start date: 2019-03-01
• Primary completion: 2019-04-01
• Completion: 2019-04-01
• First posted: 2018-08-09
• Last updated: 2018-09-11