NCT03621124

Maladaptive Adipose Tissue Activity in Cancer

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 3 (actual)
• Sponsor: Virginia Commonwealth University · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this pilot research is to study brown adipose tissue, a type of fat that increases metabolism (burns energy) during exposure to cold, and how it may contribute to the weight loss observed in cancer.

Detailed description

The purpose of this research is to study brown adipose tissue, a type of fat that increases metabolism (burns energy) during exposure to cold, and how it may contribute to the weight loss observed in cancer. Many patients affected by cancer lose weight, despite normal or increased nutrition. It may progress to the condition called "cancer-associated cachexia." Cancer associated cachexia is defined by an ongoing loss of skeletal muscle mass with or without the loss of fat mass, and may negatively affect quality of life and the ability to undergo cancer treatments. Metabolism is the breakdown of food by the body into the energy that your body needs.

Conditions

• Cancer Nos

Interventions

Type	Name	Description
PROCEDURE	Resting Energy Expenditure	During each visit, the participant will be assessed in a resting state in a stable temperature controlled environment, and will undergo tests to find out how the body adjusts its metabolism to different temperatures.
OTHER	Thermal Comfort Questionnaire	Patients will be given a questionnaire to assess their thermal response (whether they felt warmer or colder) during each study visit.

Timeline

• Start date: 2018-08-16
• Primary completion: 2020-05-20
• Completion: 2020-05-20
• First posted: 2018-08-08
• Last updated: 2026-04-13

Locations

1 site across 1 country: United States