NCT03618511

Interventions to Improve HIV Antiretroviral Therapy Adherence

Interventions to Improve HIV Antiretroviral Therapy Adherence in Sofala Province Mozambique

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 914 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will explore whether financial incentives, reminders, information about HIV/AIDS and its treatment and anti-stigma counseling help improve anti-retroviral therapy (ART) adherence among HIV infected individuals in a resource-limited environment. The interventions will be randomized in the study population in a cross-cutting design, with a control group, a financial incentive treatment group, a reminders treatment group, a treatment group that receives both the financial incentive and reminder interventions. In addition, there will be an information treatment group, a stigma-relieving treatment group and a group that receives both information and stigma-relieving interventions. The primary outcomes of interest for this study will be the adherence to ART, measured by attendance rates at clinic appointments and refill collection rates.

Conditions

• Human Immunodeficiency Virus (HIV) Infection

Interventions

Type	Name	Description
BEHAVIORAL	Financial Incentive	Financial Incentive: Participants will receive monthly financial incentives each time they refill the ART medication on time for six months
BEHAVIORAL	Reminders	Reminders: Participants will receive monthly reminder phone calls before their ART medication refill is due for six months.
BEHAVIORAL	Financial Incentive and Reminders	Interaction: Participants receive both the Financial Incentives and Reminder Calls.
BEHAVIORAL	Information	Information: show the participants a video about HIV progression, mechanism of ART, the benefit of adhering to ART.
BEHAVIORAL	Stigma-relieving	Stigma-Reliving: Upon recruitment, inform the participants of the results of a recent population survey regarding people's attitudes towards HIV, if they overestimate the social stigma related to HIV. This intervention intends to reduce the stigma-concern faced by the patients.
BEHAVIORAL	Information and Stigma-relieving	Information and Stigma-relieving: Upon recruitment, show the participants a video about HIV progression, mechanism of ART, the benefit of adhering to ART. In addition, inform the participants of the results of a recent population survey regarding people's attitudes towards HIV, if they overestimate the social stigma related to HIV. This intervention intends to reduce the stigma-concern faced by the patients.

Timeline

• Start date: 2018-08-06
• Primary completion: 2021-04-30
• Completion: 2021-04-30
• First posted: 2018-08-07
• Last updated: 2021-09-24

Locations

1 site across 1 country: Mozambique