NCT03618251

Automated Volume Assessment of Acute Stroke

Evaluation of Infarct Volumetric Software in Strokes of Less Than 24 Hours

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 406 (actual)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Stroke is a common disease. It is increasingly managed in non-specialized centers. The volume of the lesion, evaluated on the diffusion weighted imaging, is a prognostic factor of clinical progression and is useful for the treatment decision. There is therefore a real interest in having a reliable software able to detect the stroke and evaluate the volume of the cerebral infarction. The aim is to provide rapid information to the interventional neuroradiologist and optimize the care of the patient. The Alberta Stroke Program Early Computed Tomography Score currently used to predict response to treatment divides the territory of the middle cerebral artery. It has a few limitations, it is unreproducible and concerns only the territory of the middle cerebral artery. Manual volumetry is a long and also not very reproducible technique. The aim of our study is to evaluate the reproducibility and diagnostic performances of the automated segmentation software based on the diffusion weighted imaging sequence, and to compare it to manual and semi-automatic measurements.

Conditions

• Stroke, Software Verification, Diffusion Weighted MRI, Neuroimaging

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	specific MRI sequences	MRI with B 2000 of diffusion weighted imaging and the coefficient of apparent diffusion

Timeline

• Start date: 2018-03-15
• Primary completion: 2020-09-04
• Completion: 2020-12-04
• First posted: 2018-08-07
• Last updated: 2021-09-17

Locations

1 site across 1 country: France