Trials / Completed
CompletedNCT03615703
Functional MRI Study in Healthy Children Engaged in Aggressive Behaviors
Functional Neuroimaging Study to Validate the Point Subtraction Aggression Paradigm (PSAP) Task in Typically Developing Children (TDC) Aged 8-12 Years
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 17 (actual)
- Sponsor
- Supernus Pharmaceuticals, Inc. · Industry
- Sex
- All
- Age
- 8 Years – 12 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this non-interventional study is to optimize the point subtraction aggression paradigms (PSAP) task in typically developing children (TDC).
Detailed description
The PSAP is a behavioral aggression test used to evaluate behavioral response related to impulsive aggression. The task will be combined with functional MRI to establish a reliable BOLD signal during testing in developing healthy subjects (8-12 years old) and, to determine the feasibility to perform the task. Additionally, the levels of neurotransmitters Glutamate and GABA will be measured using magnetic resonance spectroscopy (MRS).
Conditions
Timeline
- Start date
- 2018-08-10
- Primary completion
- 2019-03-15
- Completion
- 2019-03-15
- First posted
- 2018-08-06
- Last updated
- 2019-06-10
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03615703. Inclusion in this directory is not an endorsement.