NCT03614754

Sacral Neuromodulation and Pudendal Somatic Afferents

The Involvement of Pudendal Somatic Afferents in Sacral Neuromodulation Assessed by Somatosensory Evoked Potentials of the Pudendal Nerve

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: Universiteit Antwerpen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Sacral neuromodulation is a well-excepted minimally invasive procedure for the treatment of overactive bladder and non-obstructive urinary retention.A tined lead with 4 stimulation electrodes is placed through the third or fourth sacral foramen and stimulates sacral roots in its vicinity. Since the sacral roots are mixed nerves, it is currently still unknown which nerve fibers are stimulated (autonomic vs somatic, afferent vs efferent) and what the mechanism of action is. This study examines the involvement of pudendal somatic afferents by measuring somatosensory evoked potentials elicited by stimulation of the pudendal nerve.

Conditions

• Overactive Bladder, Non Obstructive Urinary Retention

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Somatosensory evoked potentials	Stimulation of the pudendal nerve while recording at the sensory cortex.

Timeline

• Start date: 2017-08-01
• Primary completion: 2022-07-31
• Completion: 2022-07-31
• First posted: 2018-08-03
• Last updated: 2019-10-15

Locations

1 site across 1 country: Belgium