Clinical Trials Directory

Trials / Completed

CompletedNCT03614676

A Study of Outcomes and Events of Interest in Pregnant Women, Neonates and Infants and of RSV Surveillance

A Prospective Epidemiological Study of Pregnancy Outcomes and of Events of Interest in Pregnant Women, Neonates and Infants (PEPNI)

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
4,493 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
18 Years – 40 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to assess pregnancy outcomes, and maternal, as well as neonatal events of interest in healthy pregnant women and their new-borns. The study will also determine incidence of lower respiratory tract illness (LRTI) caused by respiratory syncytial virus (RSV) in the new-borns during their first year of life.

Conditions

Interventions

TypeNameDescription
PROCEDUREBlood sample collectionVenous blood samples will be collected from the maternal subjects at Day 1 and Day 56 of the study and at delivery.
PROCEDURECord blood sample collectionCollection of cord blood samples from maternal subjects will occur, at delivery
OTHERMaternal Diary CardCompletion of Diary Card about health by pregnant woman/ mother, from enrolment through week 6 post delivery.
PROCEDURENasal Swab collectionCollection of nasal swabs from infants with potential LRTIs, from birth to 12 months of age.
OTHERInfant Diary CardCompletion of Diary Card about health of infant from birth to 12 months of age.

Timeline

Start date
2019-05-30
Primary completion
2021-07-27
Completion
2021-07-27
First posted
2018-08-03
Last updated
2023-08-14
Results posted
2023-08-14

Locations

40 sites across 10 countries: Argentina, Bangladesh, Brazil, Colombia, Malaysia, Mexico, Panama, Philippines, South Africa, Thailand

Source: ClinicalTrials.gov record NCT03614676. Inclusion in this directory is not an endorsement.